To all those using, or planning to use, faecal immunochemical tests for haemoglobin (FIT) in bowel cancer screening programmes, there was some disturbing news last week. In British Columbia (BC), Canada, use of FIT ceased due to a problem with a reagent used in analysis of the samples. On the official website, it is stated that work to resolve this as quickly as possible is underway and the organisers will have a better idea of timing in the next few weeks: however, it could take a number of months for FIT analyses to resume. The details and consequences are very well documented.
In 2007, the International Agency for Research on Cancer|World Health Organization (IARC|WHO) concluded that the effects of shift work on the disruption of normal circadian rhythm had a probable link to breast cancer. IARC suggest that our endogenous 24-hour body clocks may be subject to interference by factors such as exposure to light at night, and it’s impact on melatonin levels may be linked to breast cancer. However, a recent meta-analysis led by Dr Ruth C. Travis published in the Journal of the National Cancer Institute concludes that night shift work may actually have very little effect on breast cancer risk.
Colorectal cancer is the fourth most common cancer in the UK and its incidence is increasing. However, survival rates are also increasing. In Scotland, age-standardised, five year survivorship rates have increased from 42.9% in 1987-91 to 64.7% in 2007-11. More people surviving after a bowel cancer diagnosis is fantastic news, but there is considerable room for improvement in both quantity and quality of years; multi-modal treatment pathways, risk of complications and the possibility of a stoma can cause prolonged physical and psychological recovery.
Once again we are nearing the end of the year, and here at the Scottish Cancer Prevention Network, we’ve invited our members, colleagues and regular SCPN Newsletter contributors to recommend what they have been reading on cancer prevention during 2016. We’ve asked each of them to recommend one paper which they thought would be valuable to share. This week our second instalment comes to us courtesy of Prof James Garden of Edinburgh University, we hope you enjoy.
Title: Pancreatic Cancer
Once again December is upon us, and here at the Scottish Cancer Prevention Network, we’ve invited our members, colleagues and regular SCPN Newsletter contributors to recommend what they have been reading on cancer prevention during 2016. We asked each of them for one paper which they thought would be valuable to share and so kicking us off is Nicola Barnstable, Diane Primrose & The Detect Cancer Early Team, we hope you enjoy.
Title: Tipping The Scales: Why Preventing Obesity Makes Economic Sense
Many thanks to all the friends of the SCPN who have given us such great suggestions for Paper of the Year. Here’s an overview in case you missed any.
- Annie Anderson: Obesity, aspirin and risk of colorectal cancer in carriers of hereditary colorectal cancer: a prospective investigation in the CAPP2 studyhttp://jco.ascopubs.org/content/early/2015/08/11/JCO.2014.58.9952.abstract
- Linda Bauld: Real‐world effectiveness of e‐cigarettes when used to aid smoking cessation: a cross‐sectional population study.http://onlinelibrary.wiley.com/doi/10.1111/add.12623/abstract
- David Brewster: Trends in the lifetime risk of developing cancer in Great Britain: comparison of risk for those born from 1930 to 1960http://www.nature.com/bjc/journal/v112/n5/full/bjc2014606a.html
- Kathy Chapman: Cancers in Australia in 2010 attributable to modifiable factors: introduction and overviewhttp://onlinelibrary.wiley.com/doi/10.1111/1753-6405.12468/abstract
- Callum Fraser: Suspected cancer: recognition and referralhttps://www.nice.org.uk/guidance/ng12
- Gill Hubbard: Exercise and Cancer: A reviewThe Journal of the American Osteopathic Association (1963); 62:596-599.
- Susan Moug: Carcinogenicity of consumption of red and processed meat.http://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(15)00444-1/fulltext
- Nanette Mutrie: Physical activity and cancer survivorshiphttps://www.youtube.com/watch?v=fOW5fQVLDTo
- Bob Steele: Comparative Effectiveness of a Multifaceted Intervention to Improve Adherence to Annual Colorectal Cancer Screening in Community Health Centershttp://archinte.jamanetwork.com/article.aspx?articleid=1881011
Last but not least, our antipodean colleague Kathy Chapman, one of Cancer Council Australia’s experts on diet, obesity, physical activity and cancer risk provides the first systematic assessment of population attributable fractions of cancer in Australia.
Title: Cancers in Australia in 2010 attributable to modifiable factors: introduction and overview
Our penultimate blog comes from Prof Bob Steele, Clinical Director, Scottish Bowel Screening Programme and our very own co-director. He has chosen a paper which discusses an innovative approach to improving rates of bowel screening in a disadvantaged population, a challenge that’s very pertinent to us here in Scotland.
Title: Comparative Effectiveness of a Multifaceted Intervention
to Improve Adherence to Annual Colorectal Cancer Screening
in Community Health Centers
Increasingly the academic community are finding alternative ways to communicate research. We are grateful to Professor Nanette Mutrie MBE, Chair in Physical Activity for Health at University of Edinburgh for sharing her opinion on the best paper (well actually presentation) of 2015 and a brilliant learning opportunity!
Title: Physical activity and cancer survivorship